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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '47c9e30b9a6e1a7d0eb0faf746db799fbf76912c628f63c9bea6287a29fa5316' 
  AND token = 'KguJcGxaaAhtAd6qkPoTcRwhoq8MLe8YNmI3LUizAEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}