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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b09b6ca5e4a660b42b143b8fe8c83d000d0a4496f0f556ba44e32d00e0b66250' 
  AND token = 'mkfNg35FlH/Tglmnt3OkljAkC96CTXUR70MTJVBKQvg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}