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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac8fb269564a6c582fc7cb4c2b68e25ed849e77e2fa23998d4e85fd31ae2feed' 
  AND token = 'PbQXTtjGcaSRH0HhkCHRlllY7rvcoqPWJY5aTcDHvH4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}