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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '202d3eba81a5e50948e67db1ab079a1dce27e0b8506870694636de575fbfa3d4' 
  AND token = '3fRKjby/4WCn21l8gND8p6fcEgLzM/JRblrvbg+AHbg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}