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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b39d9f15bcc7e76f641292a7e46656599827c340c9072d118f1b89e302fba13' 
  AND token = 'ui9vDsWRp6NcjIcExXPHb2XzOSBAqD/lAgS+Qo0+SAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}