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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '581de562400c32caf7d1af7ef658070cbec6b45e6fb5a26e9340b75fbd65b8c4' 
  AND token = 'qDUVB2CouQy7kmIfQjCJMUihmTEN438RquSpiK1vcFg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}