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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d3df54cf969d7ef341312bb2308d1281b0e5913d56770d67a6672facb600e18' 
  AND token = 'Pa+CpvLh2EMzgkASMPx3vLNAbCugo/CoIc6a4dqYrk8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}