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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18130d582d1158b18b2cf5c98bedf06a365a39b7f343f923f9458bc0e0d84002' 
  AND token = 'QKix8sOReeSdIWiBUswG7/dpjYS+p5z+tziZuBR0eRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}