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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ef12f31408fc7d8e4ed42b786844ba864e94afae1e2504be5c8346b75d50110' 
  AND token = 'Bn+J2h36HImQBGTcx3PxVUDiRiXAHDph3GFMTywefTQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}