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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d387487626ca1fdc2b76306a46cc2849f2f02453148fc26ba3bf9dd7d5e0753' 
  AND token = '/8atpYF2lsRiuVxchCTVciw6D1pir9SFgRjzOC8wtwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}