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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '222ac8f73a860ed1fbd5d585426da1aed3673d587ef6f916a11a3175436ea875' 
  AND token = 'fMKQ0CSrLu1jQfkIvSzsoTRHz6SI913qKUYfkg9MVGw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}