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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd4ff4b49d291f42baad1595e04d210306568ed897e41d03c7db9d73d2c3a689' 
  AND token = 'ATg4aQjvvm8LQLCaiYq453vUAvh+6DfaI4Q9SdN7mZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}