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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fea03822adead1aea13fff5073e64f3b56bc68108e7300f6f1bb37e5272ec2f1' 
  AND token = 'k/lD77zjbVbKYIUTqnjEg16BystgmvbRm5nUhyCFHdc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}