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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc5e8c7adb9bc6c8f65c58984f501d02d33874bba36e304d5c00bb4a667c2cbb' 
  AND token = 'pPC3plYR/+u/ITSB6K2UnXA1JAms6PT+HkYJzPtk/2g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}