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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '557e8670515cec25ec3350ed8e06bb5ac0168720355e68e2ece5c1a858c428e9' 
  AND token = 'XIoEwy8/93jGFbJWwSImGhkzBFPpwRboKTN3Nqm8Gl0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}