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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c66c7f5412136c3966d49df0c78476e6e2b406b3067b83c6d8db298db09a641' 
  AND token = 'zxJKkCtKpaQyjD7W7iNPVX63NpQ05GqfNcdRl+7FkTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}