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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a17600aa2ce1bb8e1dea7959d5f27df739a3776704e425d8927c918ba388f273' 
  AND token = 'nmRhpM0hw+DJTmVIWnc6tjbxUoXHu+Z7yr7OilIqIPM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}