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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75e8a3f2bc5bb6bfec74425eb48595bfe41a4960271e46169dc0a925bcb4efb7' 
  AND token = '5h+ePmPi1C7WvX78yfGBDV0Fqh9mrpzhh9NzUoM3lV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}