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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '132c01c279707c8c0bc15a5a0bc1e02effeeaa75751575aa4891672b7f2b05c0' 
  AND token = 'CyMBsSuMEQ51YkMfIexY2eP6BUzH2bfMDBDTDyXcKMI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}