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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a72a52722a33d59cb4b59b95fa0f703561ce50f0c19948d44009afdf6bda9027' 
  AND token = 'm83fKsNaFzMxRJLpb3DUYdRz0oQpBNAZ/Eykz2JKNTE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}