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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e53e95c844f7bdc32ff3f54880fe78e06c7debf81e5d83b52680198fd4c0cd9e' 
  AND token = 'hKtzSxXKQ0dtyia2yOkO4YTrB5nz+uVmDqz19y2TMRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}