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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d05a7d1133e2df00d42fa02dfe3f2179653ea9445066232b6a172491f8e9b64' 
  AND token = 'kvyATv3JuwRjuc1R2sooAwzYs9WOZJGznzU44KRT9iw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}