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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7018c6522dc50686e6ca773e8a422ae2d694a221ab7c2d2b8c543cce5dc55804' 
  AND token = 'JZOq7LtTAEnd4lFgg9gkUNTsTZK2tZ1FPSWUS50XWcY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}