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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'beb5964401bd207d1aeca90b645a35e7b8c5fb374798d67f4031a87f5a44510b' 
  AND token = 'ybAA0EUxON719KaCRXDNciyfiRN2OaALi8VQduLHs78=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}