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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53dcb3b2963260efd499045258234b7f63741e092b20aa7e5bf650aa213fb4a8' 
  AND token = 'GxRwlwBlmXKRwSs+cmAhJmtvTDae1gbqtea7ND3mgzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}