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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e96c66f8d32366665ce51f2ced7ead193f78c220d1681a4748b5bda7da2990ff' 
  AND token = '67YyL7bb8NpRAsqLpld//i7XznJZV6rN+CkOcpTp60Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}