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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c16a2608408f706c9785b5f1c5afd9a42dd12da048bcb38332483bf584f868ce' 
  AND token = 'Rwf5WYdHuwf2XcRzKP29j15YKRl0wPghbWVofppDjno=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}