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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5041fa5f003a11f42d685644d3c9b839a2e6c81bc3453fe3a654d27d048879fd' 
  AND token = 'M6VPUUhqjFvY50EiKp5vy1T3yc+FoBtkFK+fD8mVV70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}