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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4eb94c6a7e592a9b6bf01bf3ee3bdc7dee0611856fe74329e09c49a72e15efae' 
  AND token = 'O0VYNQOQ1jm0sRoiLoOaczY07slKhn1Ul4w+KBjJjz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}