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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f29fe97e242a6c2cad1835a85a0e61d682571c2d724decfc98398c2d354097c' 
  AND token = 'RoHEKnYJDcDp0z5RLguLpLO+2zroDV9RU5hPVaBym+k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}