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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '265ad0684d812a431e277b6ef130d78c263c20fa01ef9a650e114384d73de05f' 
  AND token = 'bBrN8xRVGVlcsWWeHaMf5p9v3n3m2fBW8ln7xAWUMaU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}