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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9722e0096fc8e7435b30ec0d36bbe5b40a756a982b8b0ffa2fb0d480121dd08' 
  AND token = '22qrepkxFSZpOdnR9jj+B6Hde7slaf6BTx14CUR98YM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}