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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ac6d01c17f92d89728b3443dfe9fbffd007c45c98d32338636e090a52f8c301' 
  AND token = 'q1/c6QxurmSSsLLV7Qa3rQtOS2/7DVnZBrnMUnaFFNo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}