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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5653a95f4c6cc3ea24b4604e15a91951c46affacca9259552ce234068e423c5' 
  AND token = 'sqYcwUuBIVlFFBEm9f/AvL2V6MDPwAM0cszy1h3IoH8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}