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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d67e45f761e1616b268c45f0a100a60f5aa097ea43b16c7260cb482b1bbfa66' 
  AND token = '6ULUyV/cwt80uLRe7lZ2B5Z6Al+Z+6oY8jIYcv2SuJk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}