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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd821b14f544c6a1e0c730fe88d96d7a92e123e7b98837614d34cc1f5d9119636' 
  AND token = 'uwV+OZ0y8fky+wFIy35cOhnxT1JavAueNDEtshLTTpc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}