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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f49e80fde6bd63fc7f3977397d4e8a7833e06b2f2a8b33051402de377187be3' 
  AND token = '6vprhH2aruGRP+60jnMLtrPMuifvtvw9M/g8stIKqrI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}