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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57e7ef9ca846857072f29f13657bef52aca6e38bbe5382b8da77a41133acb4df' 
  AND token = 'KNJralZDoTsVOhakfM7LauDvdIh2GVoRiCXXxmz6FtA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}