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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8db2bdb1b52dd87d5f93b493ca771c34c6fbff486e09955221fef78bfd93357' 
  AND token = 'xCPsne+KNXDWCF27YW+Gi7r2mGFoQStSuZBwQWNG5yw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}