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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a8ab8d03cde7952da8c2325dac38f28c7b3b3193915bccf27fecd648062eed1' 
  AND token = '8xSCN8Fl6px6BNP3uojNgWMn996qyNq6iCt3ysbHIqw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}