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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19c49720987fbd96197fa418c549bb2fa0fef11723d0e0f4ea07346c5c1475a7' 
  AND token = 'l+IMQ1UN+b/mhREQnZP2dFD0mAo8qNaAp9/yEQyL5/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}