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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '258c24adf67a79b1bc9aac4d6018eae88aba8a97db932918e160956d2d37c04f' 
  AND token = 'D1NX/UvRGSu8pZVPviF37jVVn2aFT6AIAl/Z+vqtvuo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}