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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eab7368f1dcca324582e151743d484d32c8b30f5343cb7d18c1db78b17a91703' 
  AND token = 'KmCkHlIvtrPYRgfi8t9kjTUivzyMH6Kj5sOzZhb6cu8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}