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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '227655118e7c35ad9a27e237932744de85e2a72c08de7755bcd07257d52e41a0' 
  AND token = 's+Kpdc9hxhYMFM9inCZPzwES0+u1s+A43hQ4DWCeVN4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}