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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f3f0f6e01004f950d4b390ce96a924788ab6244d83ff7210889b016d055e206' 
  AND token = 'bP2H5cgkqCx0yQyF267/CUKR1qGxOb8apRy+A3SGspA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}