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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7eb1d8980a1a6424ce94ff9fc0745b6aa74c682a5eac7d6e85745e0d06fdb09d' 
  AND token = 'dMz1td7IpcR32zY7rnraUrsB5jHRfgx/HV6VjJ0KoIw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}