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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a48dc45b0a241cb76f86281cf622964fafa892c0341fa3ac97d96e1a7940f38' 
  AND token = 'cGunlXwEDP0pcrxOtoeYwaKjikSUXeig0Q3UsMo50cY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}