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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '497600015a05efd5a2f13cb6d1ddccf215f761b2a7bf0c88d0a7a7abbe093c24' 
  AND token = '9kR/91oAUNHRiuqbeiLdLH9xatQaChX4LjbV02BTHeM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}