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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fad46f5be262978e24111fcfa8cf4c0671521f13de1cc63cf5e3a7488ed6edcb' 
  AND token = 'ioYHrerFWBM/wngVC2MSEPYWdzkJ5MF2IlvAukw8zAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}