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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '508e06d4e761a0bdd853a4eae4645f3d3213a517296e12af523bf3592be1cd1b' 
  AND token = 'bhe/rJ1s2+o0xlNPtsTFHfbaOqDC/XHDMTyzBVQ2CMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}